A Sherlock Holmes analog, Dr. Gregory House solves medical mysteries while being an unrepentant pill-popping pain in the ass of pretty much everyone. He plays mind games with colleagues and patients alike, including his best friend, oncologist James Wilson. You can call him acerbic or brutally honest, but the reality is he’s a narcissistic asshole.
He’d probably have been fired earlier but the reason he limps is because of his boss, and god damn it, he’s almost always right. It’s never lupus, after all.
Notable Queer-Centric Episodes
- Season 2, Episode 13 “Skin Deep” – A teenaged model has androgen insensitivity syndrome, a rare (1 in 10,000 births) condition where the body has no channel to process testosterone. Despite having an XY chromosome pair, and testicles (which failed to drop), her anatomy otherwise completely conforms to female norms.
- Season 5, Episode 16 “The Softer Side” – House’s team resents being made complicit in a web of lies parents have told their son when he’s brought in for treatment that may be related to his intersexuality.