From 1961 to 1965, he portrayed Kenneth Preston on the popular legal drama The Defenders, alongside E. G. Marshall. He is best known as the father Mike Brady, opposite Florence Henderson’s Carol Brady, on the ABC sitcom The Brady Bunch, which aired from 1969 to 1974. He reprised the role of Mike Brady in several later reunion programs. In 1976, he earned two Primetime Emmy Award nominations for his guest-starring role in a two-part episode of Medical Center and for his work on the miniseries Rich Man, Poor Man. The following year, Reed earned a third Emmy nomination for his role in the miniseries Roots.