A Sherlock Holmes analog, Dr. Gregory House solves medical mysteries while being an unrepentant pill-popping pain in the ass of pretty much everyone. He plays mind games with colleagues and patients alike, including his best friend, oncologist James Wilson. You can call him acerbic or brutally honest, but the reality is he’s a narcissistic asshole.
He’d probably have been fired earlier but the reason he limps is because of his boss, and god damn it, he’s almost always right. It’s never lupus, after all.